Cytochrome P450TB (CYP2C): A major monooxygenase catalyzing diclofenac 4′-hydroxylation in human liver

A simple graphical method for determining the inhibition constants of mixed, uncompetitive and non-competitive inhibitors (Short Communication)

Athel Cornish‐Bowden · Biochemical Journal · 1974 · 936 citations · Full text

Life Sciences, Pharmacology, Chemical Kinetics +16

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

Allan E. Rettie, Kenneth R. Korzekwa, Kent L. Kunze et al. · Chemical Research in Toxicology · 1992 · 602 citations

Medicine, Pharmacology, Toxicology +17

Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily.

Mary V. Relling, Toru Aoyama, Frank J. Gonzalez et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 221 citations

Medicine, Biochemistry, Pharmacology +16

Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily

Marjorie Romkes, M B Faletto, Joyce Blaisdell et al. · Biochemistry · 1991 · 209 citations

Life Sciences, Biochemistry, Molecular Biology +10

Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9

Maurice E. Veronese, Peter I. Mackenzie, Christopher J Doecke et al. · Biochemical and Biophysical Research Communications · 1991 · 206 citations

Medicine, Biochemistry, Pharmacology +11