Single-dose quinidine treatment inhibits metoprolol oxidation in extensive metabolizers

POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN

A. Mahgoub, L. G. Dring, Jeffrey R. Idle et al. · The Lancet · 1977 · 1.2K citations

Pharmacy, Biochemistry, Pharmacology +6

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

David A. Evans, A. Mahgoub, T.P. Sloan et al. · Journal of Medical Genetics · 1980 · 540 citations · Full text

Life Sciences, Genetics, Pharmacology +17

Medicine and the Law

Diana Brahams · The Lancet · 1987 · 537 citations

Law, Health Law, Jurisprudence +10

MEDICAL NEMESIS

George Discombe · The Lancet · 1974 · 377 citations

Humanities, Internal Medicine, Clinical Medicine +1

Differential stereoselective metabolism of metoprolol in extensive and poor debrisoquin metabolizers

M. S. Lennard, Geoffrey T. Tucker, J H Silas et al. · Clinical Pharmacology & Therapeutics · 1983 · 211 citations

Pharmacy, Pharmacokinetics, Pharmacology +15