J H Silas

Oxidation Phenotype — A Major Determinant of Metoprolol Metabolism and Response

M. S. Lennard, J H Silas, Stephen Freestone et al. · New England Journal of Medicine · 1982 · 279 citations

Life Sciences, Genetics, Pharmacology +13

Differential stereoselective metabolism of metoprolol in extensive and poor debrisoquin metabolizers

M. S. Lennard, Geoffrey T. Tucker, J H Silas et al. · Clinical Pharmacology & Therapeutics · 1983 · 211 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Determination of debrisoquine and its 4-hydroxy metabolite in biological fluids by gas chromatography with flame-ionization and nitrogen-selective detection

M. S. Lennard, J H Silas, A. J. Smith et al. · Journal of Chromatography A · 1977 · 155 citations

Pharmacy, Chemistry, Pharmacology +9

Clinical evaluation of Dinamap 845 automated blood pressure recorder.

J H Silas, A.T. Barker, L E Ramsay · Heart · 1980 · 126 citations · Full text

Medicine, Cardiology, Clinical Cardiology +14

Debrisoquine polymorphism and the metabolism and action of metoprolol, timolol, propranolol and atenolol

M. S. Lennard, Geoffrey T. Tucker, J H Silas et al. · Xenobiotica · 1986 · 68 citations

Medicine, Pharmacokinetics, Pharmacology +13