Concepedia

A divalent FHA/BRCT‐binding mechanism couples the MRE11–RAD50–NBS1 complex to damaged chromatin

Flurina J. Hari, Christoph Spycher, Stephanie Jungmichel, Lucijana Pavic, Manuel Stucki

EMBO Reports · 2010 · 40 citations · 17 references

DOIFull text

Open access

Concepts

References

17

MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks

Manuel Stucki, Julie A. Clapperton, Duaa H. Mohammad et al. · Cell · 2005 · 1.1K citations · Full text

, , +14

MDC1 is a mediator of the mammalian DNA damage checkpoint

Grant S. Stewart, Bin Wang, Colin R. Bignell et al. · Nature · 2003 · 877 citations

, , +12

MDC1 Maintains Genomic Stability by Participating in the Amplification of ATM-Dependent DNA Damage Signals

Zhenkun Lou, Katherine Minter‐Dykhouse, Sonia Franco et al. · Molecular Cell · 2006 · 620 citations · Full text

, , +14

DNA Damage-Induced Cell Cycle Checkpoint Control Requires CtIP, a Phosphorylation-Dependent Binding Partner of BRCA1 C-Terminal Domains

Xiaochun Yu, Junjie Chen · Molecular and Cellular Biology · 2004 · 398 citations · Full text

, , +17

Mdc1 couples DNA double‐strand break recognition by Nbs1 with its H2AX‐dependent chromatin retention

Claudia Lukas, Fredrik Melander, Manuel Stucki et al. · The EMBO Journal · 2004 · 394 citations · Full text

, , +12