Concepedia

Silencing T-bet Defines a Critical Role in the Differentiation of Autoreactive T Lymphocytes

Amy E. Lovett‐Racke, A. Rocchini, Judy Choy, Sara C. Northrop, Rehana Z. Hussain, Robert B. Ratts, Devanjan Sikder, Michael K. Racke

Immunity · 2004 · 179 citations · 38 references

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38

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Susanne J. Szabo, Sean Kim, Gina L. Costa et al. · Cell · 2000 · 3.5K citations · Full text

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

Jonathan Sherlock, Yi Chen, Craig A. Murphy et al. · Nature · 2003 · 2.9K citations

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Distinct Effects of T-bet in T <sub>H</sub> 1 Lineage Commitment and IFN-γ Production in CD4 and CD8 T Cells

Susanne J. Szabo, Brandon M. Sullivan, Claudia Stemmann et al. · Science · 2002 · 1.2K citations

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T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

Maryam Afkarian, John R. Šedý, Jianfei Yang et al. · Nature Immunology · 2002 · 1K citations

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Mice with a disrupted IFN-γ gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)

Iris Ferber, Stefan Brocke, Cariel Taylor-Edwards et al. · The Journal of Immunology · 1996 · 973 citations · Full text

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