Concepedia

A strategy of tumor treatment in mice with doxorubicin-cyclophosphamide combination based on dendritic cell activation by human double-stranded DNA preparation

Ekaterina A. Alyamkina, Anastasia S. Proskurina, Кonstantin E. Orishchenko, Yaroslav R. Efremov, Alexandr A. Ostanin, Dmitriy Ponomarenko, Stanislav N. Zagrebelniy, Mikhail A. Shurdov

Genetic Vaccines and Therapy · 2010 · 28 citations · 36 references

DOIFull text

Open access

Abstract

Thus, the set of experiments we performed showed that exogenous dsDNA, when administered on the background of pretreatment with Dox plus CP, has an antitumor effect possibly due to DC activation.

References

36

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Tyler J. Curiel, George Coukos, Linhua Zou et al. · Nature Medicine · 2004 · 5K citations

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Induction of Tumor Immunity by Removing CD25+CD4+ T Cells: A Common Basis Between Tumor Immunity and Autoimmunity

Jun Shimizu, Sayuri Yamazaki, Shimon Sakaguchi · The Journal of Immunology · 1999 · 1.5K citations · Full text

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Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte

Shyra J. Gardai, Kathleen A. McPhillips, S. Courtney Frasch et al. · Cell · 2005 · 1.4K citations

, , +9

Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody.

Shin Onizuka, Isao Tawara, Jun Shimizu et al. · PubMed · 1999 · 1.1K citations

, , +22

Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium.

Veronika Groh, Seiamak Bahram, Stefan Bauer et al. · Proceedings of the National Academy of Sciences · 1996 · 1K citations · Full text

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