Infection and Immunity · 1992 · 20 citations · 20 references
Life SciencesBiochemistryImmunologyAdaptive ImmunityAutoimmunityInnate ImmunityAdaptive Immune ResponsesAutoantigensAutoimmune InflammationBioactive Food ComponentsPolysaccharide FunctionPolysaccharide PropertiesAdjuvant Mechanism Of ActionAdjuvant MechanismsAdjuvant-induced ImmunityBacterial AdjuvantsBacterial PolysaccharidesCarbohydrate-based AdjuvantsImmunostimulatory AdjuvantsSulfated Polysaccharides
The adjuvant action of various lipopolysaccharides on immune responses to syngeneic tissue extract in mice was examined. Only lipopolysaccharides possessing the linear mannose homopolysaccharides as O-specific polysaccharides exhibited definite adjuvant action on immune responses to the autoantigens. The intensity of this adjuvant activity of lipopolysaccharide from Klebsiella O3 seemed to be the strongest.
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