Concepedia

Adjuvant Mechanisms

Adjuvant Mechanisms is a theoretical construct in immunology that denotes the specific molecular and cellular processes through which adjuvants enhance and modulate innate immune activation, distinguishing it from general immune stimuli by its intentional design to amplify, direct, and sustain pathogen-independent immune responses.

1.1K

Publications

64.8K

Citations

5.3K

Authors

1.3K

Institutions

Publications per year

2017–2026

202

Parents

Publications

1.1K

Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives

Farielle Ellouz, Arlette Adam, R Ciorbaru et al. · Biochemical and Biophysical Research Communications · 1974 · 1K citations

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Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

Mirjam Kool, Thomas Soullié, Menno van Nimwegen et al. · The Journal of Experimental Medicine · 2008 · 983 citations · Full text

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Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis

Willem van Eden, Jelle E. R. Tholet, Ruurd van der Zee et al. · Nature · 1988 · 827 citations

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Mechanisms of Action of Adjuvants

Sunita Awate, Lorne A. Babiuk, George Mutwiri · Frontiers in Immunology · 2013 · 730 citations · Full text

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Activation of Natural Killer T Cells by α-Galactosylceramide Rapidly Induces the Full Maturation of Dendritic Cells In Vivo and Thereby Acts as an Adjuvant for Combined CD4 and CD8 T Cell Immunity to a Coadministered Protein

Shin‐ichiro Fujii, Kanako Shimizu, C. Smith et al. · The Journal of Experimental Medicine · 2003 · 710 citations · Full text

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1–5 of 1.1K

Authors

5.3K

  1. IA
    Ichiro Azuma

    Hokkaido University, Japan

    26 publications · 1.4K citations

    20

    h-index

  2. LC
    L Chedid

    Institut Pasteur, France

    22 publications · 1K citations

    17

    h-index

  3. TS
    Tetsuo Shiba

    The University of Osaka, Japan

    11 publications · 530 citations

    11

    h-index

  4. RR
    Rino Rappuoli

    Novartis (Italy), Italy

    11 publications · 1.4K citations

    11

    h-index

  5. YY
    Yuichi Yamamura

    The University of Osaka, Japan

    11 publications · 300 citations

    11

    h-index

1–5 of 5.3K

Institutions

1.3K

  1. The University of Osaka

    Osaka, Japan

    25 h-index

    190 publications

    8.6K citations

  2. Utrecht University

    Utrecht, The Netherlands

    18 h-index

    64 publications

    6K citations

  3. Institut Pasteur

    Paris, France

    18 h-index

    67 publications

    5.4K citations

  4. Harvard University

    Cambridge, United States

    16 h-index

    38 publications

    2.6K citations

  5. National Institutes of Health

    Bethesda, United States

    15 h-index

    58 publications

    7.4K citations

  6. Zhejiang University

    Hangzhou, China

    15 h-index

    85 publications

    2.3K citations

  7. Chinese Academy of Sciences

    Beijing, China

    13 h-index

    28 publications

    1.5K citations

  8. University of Gothenburg

    Gothenburg, Sweden

    12 h-index

    43 publications

    2.2K citations

1–8 of 1.3K

Venues

  1. The Journal of Immunology

    JI · 104 publications · 9.7K citations

    51

    h-index

  2. Vaccine

    80 publications · 4.6K citations

    40

    h-index

  3. PubMed

    Repository · 95 publications · 4.2K citations

    34

    h-index

  4. Infection and Immunity

    IAI · 63 publications · 3.2K citations

    32

    h-index

  5. European Journal of Immunology

    EJI · 35 publications · 3.1K citations

    25

    h-index

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