Concepedia

No Circadian Variation of Dihydropyrimidine Dehydrogenase, Uridine Phosphorylase, β-Alanine, and 5-Fluorouracil During Continuous Infusion of 5-Fluorouracil

André B. P. Kuilenburg, R.L. Poorter, Godefridus J. Peters, A. H. van Gennip, Henk van Lenthe, A. E. M. Stroomer, Kees Smid, Paul Noordhuis, Piet Bakker, C.H.N. Veenhof

Advances in experimental medicine and biology · 1998 · 12 citations · 9 references

DOI

Concepts

References

9

Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion.

Barry Harris, Seng-Jaw Soong, Robert B. Diasio · PubMed · 1990 · 445 citations

, , +17

Population study of dihydropyrimidine dehydrogenase in cancer patients.

M C Etienne, J.-L. Lagrange, O. Dassonville et al. · Journal of Clinical Oncology · 1994 · 431 citations

Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients.

Ronald A. Fleming, G. Milano, Antoine Thyss et al. · PubMed · 1992 · 235 citations

, , +16

Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma

Godefridus J. Peters, J. Lankelma, Rob Kok et al. · Cancer Chemotherapy and Pharmacology · 1993 · 106 citations

, , +9

Circadian rhythm of rat liver dihydropyrimidine dehydrogenase

Barry Harris, Ruiling Song, You‐Jian He et al. · Biochemical Pharmacology · 1988 · 75 citations

, , +7