Concepedia

Paul Noordhuis

PN

Statistics

Publications

61

Citations

4.1K

H-Index

34

Active since

1986

Affiliations

Amsterdam UMC Location Vrije Universiteit Amsterdam(Current)

University of Amsterdam

Vrije Universiteit Amsterdam

The Netherlands Cancer Institute

University of Oslo

Paul Noordhuis is an author at Amsterdam UMC Location Vrije Universiteit Amsterdam specializing in medicine, pharmacology, and cancer research.

Top concepts

Publications per year

1986–2019

61

Publications

61

Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2.

Jan Hendrik Hooijberg, Henk J. Broxterman, Marcel Kool et al. · PubMed · 1999 · 445 citations

, , +14

5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers

Paul Noordhuis, U. Holwerda, C.L. van der Wilt et al. · Annals of Oncology · 2004 · 257 citations · Full text

, , +6

Circumvention of Methotrexate Resistance in Childhood Leukemia Subtypes by Rationally Designed Antifolates

Marianne G. Rots, Rob Pieters, Godefridus J. Peters et al. · Blood · 1999 · 214 citations

Circumvention of Methotrexate Resistance in Childhood Leukemia Subtypes by Rationally Designed Antifolates

Marianne G. Rots, Rob Pieters, Godefridus J. Peters et al. · Blood · 1999 · 186 citations

A Structurally Altered Human Reduced Folate Carrier with Increased Folic Acid Transport Mediates a Novel Mechanism of Antifolate Resistance

Gerrit Jansen, Robert Mauritz, Stavit Drori et al. · Journal of Biological Chemistry · 1998 · 163 citations · Full text

, , +14

1–5 of 61