Kees Smid

5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers

Paul Noordhuis, U. Holwerda, C.L. van der Wilt et al. · Annals of Oncology · 2004 · 257 citations · Full text

Oncogenic Agent, Synthase Inhibition, Molecular Biology +6

Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil.

Godefridus J. Peters, C.L. van der Wilt, C.J. van Groeningen et al. · Journal of Clinical Oncology · 1994 · 195 citations

<i>In vivo</i> Induction of Resistance to Gemcitabine Results in Increased Expression of Ribonucleotide Reductase Subunit M1 as the Major Determinant

Andries M. Bergman, Paul P. Eijk, Veronique W.T. Ruiz van Haperen et al. · Cancer Research · 2005 · 180 citations · Full text

Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia

Mina Maftouh, Abolfazl Avan, Rocco Sciarrillo et al. · British Journal of Cancer · 2013 · 172 citations · Full text

Molecular Mechanisms Underlying the Synergistic Interaction of Erlotinib, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, with the Multitargeted Antifolate Pemetrexed in Non-Small-Cell Lung Cancer Cells

Elisa Giovannetti, Clara Lemos, Christina Tekle et al. · Molecular Pharmacology · 2008 · 158 citations