C.J. van Groeningen

5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers

Paul Noordhuis, U. Holwerda, C.L. van der Wilt et al. · Annals of Oncology · 2004 · 261 citations · Full text

Medicine, Molecular Biology, Oncology +12

Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil.

Godefridus J. Peters, C.L. van der Wilt, C.J. van Groeningen et al. · Journal of Clinical Oncology · 1994 · 195 citations

Medicine, Oncology, Pharmacology +15

Extended adjuvant aromatase inhibition after sequential endocrine therapy (DATA): a randomised, phase 3 trial

Vivianne C. G. Tjan‐Heijnen, Irene E.G. van Hellemond, Petronella G.M. Peer et al. · The Lancet Oncology · 2017 · 158 citations

Medicine, Endocrinology, Pharmacology +14

Pharmacokinetics of 5-fluorouracil assessed with a sensitive mass spectrometric method in patients on a dose escalation schedule.

C.J. van Groeningen, Herbert M. Pinedo, J. Heddes et al. · PubMed · 1988 · 133 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma

Godefridus J. Peters, J. Lankelma, Rob Kok et al. · Cancer Chemotherapy and Pharmacology · 1993 · 106 citations

Medicine, Pharmacokinetics, Pharmacology +13