Concepedia

Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma

Godefridus J. Peters, J. Lankelma, Rob Kok, Paul Noordhuis, C.J. van Groeningen, C.L. van der Wilt, Sybren Meyer, Herbert M. Pinedo

Cancer Chemotherapy and Pharmacology · 1993 · 106 citations · 32 references

DOI

Concepts

References

32

Facilitated transport of uracil and 5‐fluorouracil, and permeation of orotic acid into cultured mammalian cells

Robert M. Wohlhueter, R. Scott McIvor, Peter G.W. Plagemann · Journal of Cellular Physiology · 1980 · 165 citations

, , +17

5-Flourouracil metabolism monitored in vivo by 19F NMR

A. N. Stevens, Peter G. Morris, R. A. Iles et al. · British Journal of Cancer · 1984 · 158 citations · Full text

, , +10

Pharmacokinetics of 5-fluorouracil assessed with a sensitive mass spectrometric method in patients on a dose escalation schedule.

C.J. van Groeningen, Herbert M. Pinedo, J. Heddes et al. · PubMed · 1988 · 133 citations

, , +14

Metabolites of 5-fluorouracil in plasma and urine, as monitored by 19F nuclear magnetic resonance spectroscopy, for patients receiving chemotherapy with or without methotrexate pretreatment.

William E. Hull, Rüdiger E. Port, Richard Herrmann et al. · PubMed · 1988 · 131 citations

, , +16

Tumor trapping of 5-fluorouracil: in vivo 19F NMR spectroscopic pharmacokinetics in tumor-bearing humans and rabbits.

Walter Wolf, Cary A. Presant, Kenneth L. Servis et al. · Proceedings of the National Academy of Sciences · 1990 · 128 citations

, , +12