Paul P. Eijk

DNA copy number analysis of fresh and formalin-fixed specimens by shallow whole-genome sequencing with identification and exclusion of problematic regions in the genome assembly

Ilari Scheinin, Daoud Sie, Henrik Bengtsson et al. · Genome Research · 2014 · 548 citations · Full text

Genetics, Genetic Epidemiology, Pathology +23

Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures

Catherine Naughton, Nicolaos Avlonitis, Samuel Corless et al. · Nature Structural & Molecular Biology · 2013 · 399 citations · Full text

Chromatin, Transcriptional Regulation, Chromatin Structure +11

Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping

Paula J. P. de Vree, Elzo de Wit, Monique van de Heijning et al. · Nature Biotechnology · 2014 · 294 citations

Long-read Sequencing, Sequencing, Functional Genomics +13

The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids

Philip C. De Witt Hamer, Angela A.G. van Tilborg, Paul P. Eijk et al. · Oncogene · 2007 · 218 citations · Full text

Developmental Biology, Human Malignant Glioma, Tumor Heterogeneity +9

<i>In vivo</i> Induction of Resistance to Gemcitabine Results in Increased Expression of Ribonucleotide Reductase Subunit M1 as the Major Determinant

Andries M. Bergman, Paul P. Eijk, Veronique W.T. Ruiz van Haperen et al. · Cancer Research · 2005 · 180 citations · Full text