Concepedia

Identification of 2-(4-pyridyl)thienopyridinones as GSK-3β inhibitors

Gabriella Gentile, Giovanni Bernasconi, Alfonso Pozzan, Giancarlo Merlo, Paola Marzorati, Paul Bamborough, B.D. Bax, Angela Bridges, Caroline Brough, Paul Carter,

Bioorganic & Medicinal Chemistry Letters · 2011 · 25 citations · 7 references

DOIFull text

Open access

Concepts

References

7

Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

Peter Ertl, Bernhard Rohde, Paul M. Selzer · Journal of Medicinal Chemistry · 2000 · 3K citations

, , +15

A molecular mechanism for the effect of lithium on development.

Peter S. Klein, Douglas A. Melton · Proceedings of the National Academy of Sciences · 1996 · 2.3K citations

, , +11

Modeling Water Molecules in Protein−Ligand Docking Using GOLD

Marcel L. Verdonk, Gianni Chessari, Jason C. Cole et al. · Journal of Medicinal Chemistry · 2005 · 390 citations

, , +16

Structural Characterization of the GSK-3β Active Site Using Selective and Non-selective ATP-mimetic Inhibitors

J. A. Bertrand, Sandrine Thieffine, Anna Vulpetti et al. · Journal of Molecular Biology · 2003 · 314 citations

, , +12

The Structure of Phosphorylated GSK-3β Complexed with a Peptide, FRATtide, that Inhibits β-Catenin Phosphorylation

B.D. Bax, Paul S. Carter, Ceri Lewis et al. · Structure · 2001 · 199 citations · Full text

, , +9