Conformational Drug Determinants of the Sequence Specificity of Drug-stimulated Topoisomerase II DNA Cleavage

Giovanni Capranico, Manlio Palumbo, Stella Tinelli, +3

Journal of Molecular Biology

ChromatinDrug TargetBiochemistryNatural SciencesOligonucleotide +7

A Combinatorial Approach to [1,5]Benzothiazepine Derivatives as Potential Antibacterial Agents

Fabrizio Micheli, Fabio Degiorgis, Aldo Feriani, +4

Journal of Combinatorial Chemistry

Combinatorial ChemistrySolid PhaseBioorganic ChemistryCombinatorial LibrariesPharmacotherapy +16

5-Aryl-4-carboxamide-1,3-oxazoles: Potent and selective GSK-3 inhibitors

Gabriella Gentile, Giancarlo Merlo, Alfonso Pozzan, +11

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryMedicineMechanism Of ActionPharmacological AgentPharmacotherapy +4

Angular Furoquinolinones, Psoralen Analogs:  Novel Antiproliferative Agents for Skin Diseases. Synthesis, Biological Activity, Mechanism of Action, and Computer-Aided Studies

P. Rodighiero, Adriano Guiotto, Adriana Chilin, +7

Journal of Medicinal Chemistry

Molecular BiologyEscherichia ColiOrganic ChemistryDuplex MacromoleculeDermatology +20

Pyrrolo[1,2-a]pyrazine and pyrazolo[1,5-a]pyrazine: Novel, potent, and selective series of Vasopressin1b receptor antagonists

Roberto Arban, Federica Bianchi, Alberto Buson, +9

Bioorganic & Medicinal Chemistry Letters

MedicineMechanism Of ActionPharmacological AgentVasopressin1b Receptor AntagonistsPharmacotherapy +3

Deep Learning Applied to Ligand-Based De Novo Drug Design

Ferruccio Palazzesi, Alfonso Pozzan

Methods in molecular biology

Drug TargetDeep Learning AppliedDe Novo Drug DesignDrug DesignMedicine +6

Identification, biological characterization and pharmacophoric analysis of a new potent and selective NK1 receptor antagonist clinical candidate

Romano Di Fabio, Giuseppe Alvaro, Simone Braggio, +13

Bioorganic & Medicinal Chemistry

Biological CharacterizationNovel TherapyFunctional SelectivityMedicineImmunology +7

Identification of 2-(4-pyridyl)thienopyridinones as GSK-3β inhibitors

Gabriella Gentile, Giovanni Bernasconi, Alfonso Pozzan, +10

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryBiochemistryMedicineGsk-3β Inhibitors +6

A novel ketolide class: Synthesis and antibacterial activity of a lead compound

Daniele Andreotti, Ilaria Bientinesi, Stefano Biondi, +7

Bioorganic & Medicinal Chemistry Letters

MedicineAntibacterial ActivityDrug DiscoveryNovel Ketolide ClassLead Identification +7

Fast Atom Bombardment Mass Spectrometry in the Study of Dopamine Melanogenesis Intermediates

Graziella Allegri, Roberto Arban, Carlo Costa, +4

Pigment Cell Research