Concepedia

3′,4′-trans-Linked bicyclic nucleosides locked in S-type conformations

Helena Thomasen, Michael Meldgaard, Morten Freitag, Michael Petersen, Jesper Wengel, Poul Nielsen

Chemical Communications · 2002 · 21 citations · 22 references

DOI

Concepts

Abstract

A novel class of 3',4'-trans-linked bicyclic nucleosides with locked S-type furanose conformations is introduced by synthesis of two model derivatives; one was obtained by cyclic ether formation and the other by ring-closing metathesis methodology.

References

22

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