Concepedia

Modulation of TRAIL resistance in colon carcinoma cells: Different contributions of DR4 and DR5

Caroline MM van Geelen, Bodvaël Pennarun, Phuong Le, Elisabeth G.E. de Vries, Steven de Jong

BMC Cancer · 2011 · 35 citations · 45 references

DOIFull text

Open access

Abstract

These results highlight a critical difference between DR4- and DR5-mediated apoptotic signaling modulation, with possible implications for future combinatorial regimens.

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