Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family

Robert Pitti, Scot A. Marsters, Siegfried Ruppert, +3

Journal of Biological Chemistry

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

James P. Sheridan, Scot A. Marsters, Robert Pitti, +10

Science

Signal TransductionSignaling PathwayG Protein-coupled ReceptorMedicineReceptor Tyrosine Kinase +13

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

Robert Pitti, Scot A. Marsters, David A. Lawrence, +15

Nature

Genomic AmplificationEngineeringDecoy ReceptorMedicineBiomarker Target +10

A novel receptor for Apo2L/TRAIL contains a truncated death domain

Scot A. Marsters, James P. Sheridan, Robert Pitti, +8

Current Biology

Signal TransductionSignaling PathwayTruncated Death DomainG Protein-coupled ReceptorMedicine +6

Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL

Klaus W. Wagner, Elizabeth A. Punnoose, Thomas Januario, +13

Nature Medicine

Cancer ResearchG Protein-coupled ReceptorMedicineApoptosisCell Death +7

Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling

Zhaoyu Jin, Yun Li, Robert Pitti, +4

Cell

Cullin3-based PolyubiquitinationSignal TransductionSignaling PathwayCell RegulationApoptosis +8

Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI

Scot A. Marsters, Minhong Yan, Robert Pitti, +3

Current Biology

Tnf Homologues BlysMolecular PhysiologyAutoimmune DiseaseSignal TransductionSignaling Pathway +7

An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells

Maia Vinogradova, Victor Gehling, Amy Gustafson, +32

Nature Chemical Biology

Drug-tolerant Cancer CellsMedicineAnti-cancer AgentTumor SuppressorCancer Treatment +5

Platelet glycoprotein IIb-IIIa protein antagonists from snake venoms: evidence for a family of platelet-aggregation inhibitors.

Mark S. Dennis, William J. Henzel, Robert Pitti, +5

Proceedings of the National Academy of Sciences

ImmunologyPharmacotherapyChemical BiologyPlatelet AggregationMolecular Pharmacology +17

Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure

Gulfem D. Guler, Charles Tindell, Robert Pitti, +21

Cancer Cell

Cell RegulationOncogenic AgentMedicineCell DeathLethal Drug Exposure +7