An algebra-based method for inferring gene regulatory networks

Paola Vera‐Licona, Abdul Salam Jarrah, Luis David García Puente, John McGee, Reinhard Laubenbacher

BMC Systems Biology · 2014 · 32 citations · 53 references

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Abstract

Boolean polynomial dynamical systems provide a powerful modeling framework for the reverse engineering of gene regulatory networks, that enables a rich mathematical structure on the model search space. A C++ implementation of the method, distributed under LPGL license, is available, together with the source code, at http://www.paola-vera-licona.net/Software/EARevEng/REACT.html.

References

53