Concepedia

The structure of P‐TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

Sonja Baumli, Graziano Lolli, E.D. Lowe, Sonia Troiani, Luisa Rusconi, Alex N. Bullock, J.E. Debreczeni, Stefan Knapp, L.N. Johnson

The EMBO Journal · 2008 · 353 citations · 42 references

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42

An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor

Xuewu Zhang, Jodi Gureasko, Kui Shen et al. · Cell · 2006 · 1.6K citations · Full text

, , +15

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

Philip D. Jeffrey, Alicia A. Russo, Kornélia Polyák et al. · Nature · 1995 · 1.4K citations

, , +9

A Novel CDK9-Associated C-Type Cyclin Interacts Directly with HIV-1 Tat and Mediates Its High-Affinity, Loop-Specific Binding to TAR RNA

Ping Wei, Mitchell Garber, Shi-Min Fang et al. · Cell · 1998 · 1.2K citations · Full text

, , +8

Crystal structure of the p27Kip1 cyclin-dependent-kinase inibitor bound to the cyclin A–Cdk2 complex

Alicia A. Russo, Philip D. Jeffrey, Andrea K. Patten et al. · Nature · 1996 · 900 citations

, , +16

7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

Van Trung Nguyen, Tamás Kiss, Annemieke A. Michels et al. · Nature · 2001 · 706 citations

, , +10