Mannose‐mediated inhibitory effects of <scp>PA</scp>‐<scp>MSHA</scp> on invasion and metastasis of hepatocellular carcinoma via <scp>EGFR</scp>/Akt/IκBβ/<scp>NF</scp>‐κB pathway

Abstract

Our study demonstrated the essential role of EGFR/Akt/IκBβ/NF-κB pathway in the inhibitory effect of PA-MSHA on invasion and metastasis of HCC through suppressing EMT, and revealed an attractive prospect of PA-MSHA as a novel candidate agent in the treatment of HCC.