Jason A. Gustin

NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase

Osman Nidai Özeş, Lindsey D. Mayo, Jason A. Gustin et al. · Nature · 1999 · 2.2K citations

Life Sciences, Cell Biology, Immunology +16

A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1

Osman Nidai Özeş, Hakan Akça, Lindsey D. Mayo et al. · Proceedings of the National Academy of Sciences · 2001 · 380 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Cell Type-specific Expression of the IκB Kinases Determines the Significance of Phosphatidylinositol 3-Kinase/Akt Signaling to NF-κB Activation

Jason A. Gustin, Osman N. Özeş, Hakan Akça et al. · Journal of Biological Chemistry · 2004 · 199 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +15

Tumor Necrosis Factor Employs a Protein-tyrosine Phosphatase to Inhibit Activation of KDR and Vascular Endothelial Cell Growth Factor-induced Endothelial Cell Proliferation

Li‐Wha Wu, James D. Dunbar, Osman N. Özeş et al. · Journal of Biological Chemistry · 2000 · 127 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

The PTEN Tumor Suppressor Protein Inhibits Tumor Necrosis Factor-induced Nuclear Factor κB Activity

Jason A. Gustin, Tomohiko Maehama, Jack E. Dixon et al. · Journal of Biological Chemistry · 2001 · 108 citations · Full text

Life Sciences, Cell Biology, Oncology +15