Associations between<i>CYP2B6</i>Polymorphisms and Pharmacokinetics after a Single Dose of Nevirapine or Efavirenz in African Americans

Abstract

Selective pressure for drug-resistant HIV-1 after administration of single-dose nevirapine may not differ substantially according to CYP2B6 516/983 genotype. Additional polymorphisms, genes, and populations warrant further study.