Usha N. Menon

A Selective Allosteric Potentiator of the M₁Muscarinic Acetylcholine Receptor Increases Activity of Medial Prefrontal Cortical Neurons and Restores Impairments in Reversal Learning

Jana K. Shirey, Ashley E. Brady, Paulianda J. Jones et al. · Journal of Neuroscience · 2009 · 238 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Discovery of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Reveals Chemical and Functional Diversity and In Vivo Activity in Rat Behavioral Models of Anxiolytic and Antipsychotic Activity

Alice L. Rodriguez, Mark D. Grier, Carrie K. Jones et al. · Molecular Pharmacology · 2010 · 179 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Associations between<i>CYP2B6</i>Polymorphisms and Pharmacokinetics after a Single Dose of Nevirapine or Efavirenz in African Americans

David W. Haas, Tebeb Gebretsadik, Gail Mayo et al. · The Journal of Infectious Diseases · 2009 · 104 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +15

Synthesis and Evaluation of a Series of Heterobiarylamides That Are Centrally Penetrant Metabotropic Glutamate Receptor 4 (mGluR4) Positive Allosteric Modulators (PAMs)

Darren W. Engers, Colleen M. Niswender, C. David Weaver et al. · Journal of Medicinal Chemistry · 2009 · 81 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of 2‐(2‐Benzoxazoyl amino)‐4‐Aryl‐5‐Cyanopyrimidine as Negative Allosteric Modulators (NAMs) of Metabotropic Glutamate Receptor 5 (mGlu₅): From an Artificial Neural Network Virtual Screen to an In Vivo Tool Compound

Ralf Mueller, Eric S. Dawson, Jens Meiler et al. · ChemMedChem · 2012 · 45 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11