Gene Silencing of Complement C5a Receptor Using siRNA for Preventing Ischemia/Reperfusion Injury

RNA interference in adult mice

Anton P. McCaffrey, Leonard Meuse, Thu-Thao T. Pham et al. · Nature · 2002 · 1.1K citations

Rna Interference, Genetics, Rna Biology +3

Efficient delivery of siRNA for inhibition of gene expression in postnatal mice

David L. Lewis, James E. Hagstrom, A. G. Loomis et al. · Nature Genetics · 2002 · 552 citations

Developmental Biology, Postnatal Mice, Gene Delivery +7

Predominant role for C5b-9 in renal ischemia/reperfusion injury

Wuding Zhou, Conrad A. Farrar, Katsushige Abe et al. · Journal of Clinical Investigation · 2000 · 457 citations · Full text

Caspase 8 small interfering RNA prevents acute liver failure in mice

Lars Zender, Sebastian Hütker, Christian Liedtke et al. · Proceedings of the National Academy of Sciences · 2003 · 384 citations · Full text

Liver Fibrosis, Apoptosis, Immunology +21

The classical pathway is the dominant complement pathway required for innate immunity to<i>Streptococcus pneumoniae</i>infection in mice

Jeremy Brown, Tracy Hussell, Sarah M. Gilliland et al. · Proceedings of the National Academy of Sciences · 2002 · 364 citations · Full text

Microbial Pathogens, Innate Immune System, Immunology +18