Concepedia

Efficient delivery of siRNA for inhibition of gene expression in postnatal mice

David L. Lewis, James E. Hagstrom, A. G. Loomis, Jon A. Wolff, Hans Herweijer

Nature Genetics · 2002 · 552 citations · 14 references

DOI

Concepts

References

14

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Andrew Fire, Siqun Xu, Mary K. Montgomery et al. · Nature · 1998 · 15.3K citations · Full text

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.4K citations

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RNA interference is mediated by 21- and 22-nucleotide RNAs

Sayda M. Elbashir, Winfried Lendeckel, Thomas Tuschl · Genes & Development · 2001 · 3.3K citations · Full text

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

Scott M. Hammond, Emily Bernstein, David Beach et al. · Nature · 2000 · 3K citations

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RNAi

Phillip D. Zamore, Thomas Tuschl, Phillip A. Sharp et al. · Cell · 2000 · 2.6K citations · Full text