S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice

Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695

M. Azhar Chishti, Dun-Shen Yang, Christopher Janus et al. · Journal of Biological Chemistry · 2001 · 954 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Age-Specific Epigenetic Drift in Late-Onset Alzheimer's Disease

Sun-Chong Wang, Beatrice Oelze, Axel Schumacher · PLoS ONE · 2008 · 469 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production

Andrea Fuso, Laura Seminara, Rosaria A. Cavallaro et al. · Molecular and Cellular Neuroscience · 2004 · 407 citations

Life Sciences, Biochemistry, Molecular Biology +17

A Controlled Trial of Homocysteine Lowering and Cognitive Performance

Jennifer McMahon, Tim Green, C. Murray Skeaff et al. · New England Journal of Medicine · 2006 · 403 citations · Full text

Medicine, Geriatric Medicine, Nutritional Sciences +16

Epigenetic Differences in Cortical Neurons from a Pair of Monozygotic Twins Discordant for Alzheimer's Disease

Diego Mastroeni, Ann C. McKee, Andrew Grover et al. · PLoS ONE · 2009 · 293 citations · Full text

Life Sciences, Genetics, Neuroscience +17