Effects of substrate feed rates on heterologous protein expression by Pichia pastoris in DO-stat fed-batch fermentation

Control of fed-batch fermentations

Sang Yup Lee, Sunwon Park, Anton P. J. Middelberg · Biotechnology Advances · 1999 · 287 citations

Engineering, Biotechnology, Chemical Engineering +12

High Cell-Density Fermentation

Jayne Stratton, Vijay Chiruvolu, Michael M. Meagher · Methods in molecular biology · 1998 · 275 citations

Engineering, Biotechnology, Microbiology +17

Isolation of alcohol oxidase and two other methanol regulatable genes from the yeast Pichia pastoris.

S.B. Ellis, Paul F. Brust, P J Koutz et al. · Molecular and Cellular Biology · 1985 · 272 citations · Full text

Life Sciences, Microbiology, Molecular Biology +12

Advances in the use of Pichia pastoris for high-level gene expression

Mike Romanos · Current Opinion in Biotechnology · 1995 · 251 citations

Life Sciences, Biological Engineering, Biotechnology +14

ModelingPichia pastoris growth on methanol and optimizing the production of a recombinant protein, the heavy-chain fragment C of botulinum neurotoxin, serotype A

Wenhui Zhang, Mark A. Bevins, Bradley A. Plantz et al. · Biotechnology and Bioengineering · 2000 · 234 citations

Life Sciences, Biotechnology, Microbiology +17