Comparing myotoxic effects of squalene synthase inhibitor, T-91485, and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors in human myocytes

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Pharmacy, Internal Medicine, Pharmacology +12

A New Sulfonated Tetrazolium Salt That Produces a Highly Water-Soluble Formazan Dye.

Munetaka Ishiyama, Masanobu Shiga, Kazumi Sasamoto et al. · Chemical and Pharmaceutical Bulletin · 1993 · 487 citations · Full text

Pharmacy, Biochemistry, Chemical Biology +8

Statin-induced inhibition of the Rho-signaling pathway activates PPARα and induces HDL apoA-I

Geneviève Martin, Hélène Duez, Christophe Blanquart et al. · Journal of Clinical Investigation · 2001 · 418 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +16

3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Isoprenylation Inhibitors Induce Apoptosis of Vascular Smooth Muscle Cells in Culture

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Life Sciences, Biochemistry, Pharmacology +15

Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer.

Alain Thibault, Dvorit Samid, A Tompkins et al. · PubMed · 1996 · 361 citations

Medicine, Oncology, Pharmacology +10