Activation of Human Peroxisome Proliferator-Activated Receptor (PPAR) Subtypes by Pioglitazone

Junichi Sakamoto, Hiroyuki Kimura, Shinji Moriyama, +4

Biochemical and Biophysical Research Communications

MedicinePhysiologyReceptor (Biochemistry)Clinical PharmacologyExperimental Pharmacology +4

Reduction of Insulin Resistance in Obese and/or Diabetic Animals by 5-[4-(1-Methylcyclohexylmethoxy)benzyl]-thiazolidine-2,4-dione (ADD-3878, U-63,287, Ciglitazone), a New Antidiabetic Agent

Takeshi Fujita, Yasuo Sugiyama, Shigehisa Taketomi, +4

Diabetes

Diabetic AnimalsMetabolic DisorderNew Antidiabetic AgentInsulin SignalingObesity +18

Evolution of the archaeal rhodopsins: evolution rate changes by gene duplication and functional differentiation

Kunio Ihara, Tohru Umemura, Izumi Katagiri, +4

Journal of Molecular Biology

BiologyPhylogeneticsEvolution Rate ChangesNatural SciencesEvolutionary Biology +9

Studies on antidiabetic agents. II. Synthesis of 5-(4-(1-methylcyclohexylmethoxy)-benzyl)thiazolidine-2,4-dione (ADD-3878) and its derivatives.

Takashi Sohda, Katsutoshi Mizuno, Eiko Imamiya, +3

Chemical and Pharmaceutical Bulletin

Derivative (Chemistry)Medicinal ChemistryPharmaceutical ScienceBioorganic ChemistryDerivatives +13

Implantable Collamer Lens Sizing Method Based on Swept-Source Anterior Segment Optical Coherence Tomography

Tomoaki Nakamura, Naoki Isogai, Takashi Kojima, +2

American Journal of Ophthalmology

OphthalmologyOptical Coherence TomographyGlaucomaBiomedical EngineeringMedicine +2

Optimization of implantable collamer lens sizing based on swept-source anterior segment optical coherence tomography

Tomoaki Nakamura, Naoki Isogai, Takashi Kojima, +2

Journal of Cataract & Refractive Surgery

Posterior Chamber Phakic Intraocular Lens Implantation for the Correction of Myopia and Myopic Astigmatism: A Retrospective 10-Year Follow-up Study

Tomoaki Nakamura, Naoki Isogai, Takashi Kojima, +2

American Journal of Ophthalmology

Ophthalmic SurgeryOphthalmologyExperimental OphthalmologyOculoplasticsMyopic Astigmatism +5

Studies on antidiabetic agents. I. Synthesis of 5-(4-(2-methyl-2-phenylpropoxy)-benzyl)thiazolidine-2,4-dione (AL-321) and related compounds.

Takashi Sohda, Katsutoshi Mizuno, H. TAWADA, +3

Chemical and Pharmaceutical Bulletin

Bioorganic ChemistryAntidiabetic AgentsI. SynthesisRelated CompoundsPharmaceutical Chemistry +14

Synthesis of Novel 4,1-Benzoxazepine Derivatives as Squalene Synthase Inhibitors and Their Inhibition of Cholesterol Synthesis

Takashi Miki, Masakuni Kori, Hiroshi Mabuchi, +5

Journal of Medicinal Chemistry

Comparing myotoxic effects of squalene synthase inhibitor, T-91485, and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors in human myocytes

Tomoyuki Nishimoto, Ryuichi Tozawa, Yuichiro Amano, +3

Biochemical Pharmacology

Human MyocytesBiochemistryMedicineToxicologyPharmacotherapy +8