Hiroyuki Kimura

Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma.

Hiroyuki Kimura, R. D. Braun, E T Ong et al. · PubMed · 1996 · 372 citations

Biological Microenvironments, Cancer Biology, Cellular Physiology +22

Activation of Human Peroxisome Proliferator-Activated Receptor (PPAR) Subtypes by Pioglitazone

Junichi Sakamoto, Hiroyuki Kimura, Shinji Moriyama et al. · Biochemical and Biophysical Research Communications · 2000 · 310 citations

Medicine, Physiology, Receptor (Biochemistry) +6

Microvascular studies on the origins of perfusion-limited hypoxia.

Mark W. Dewhirst, Hiroyuki Kimura, Wingfield Rehmus et al. · PubMed · 1996 · 163 citations

Cellular Physiology, Perfusion-limited Hypoxia, Blood Flow +16

Novel Inhibitor of p38 MAP Kinase as an Anti-TNF-α Drug:  Discovery of <i>N</i>-[4-[2-Ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridyl]benzamide (TAK-715) as a Potent and Orally Active Anti-Rheumatoid Arthritis Agent

Seiji Miwatashi, Yasuyoshi Arikawa, Etsuo Kotani et al. · Journal of Medicinal Chemistry · 2005 · 145 citations · Full text

Novel Inhibitor, P38 Map Kinase, Immunology +23

A comparison of vital capacity breath and tidal breathing techniques for induction of anaesthesia with high sevoflurane concentrations in nitrous oxide and oxygen

Masaki Yurino, Hiroyuki Kimura · Anaesthesia · 1995 · 111 citations · Full text