ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer

HER2 (neu) Signaling Increases the Rate of Hypoxia-Inducible Factor 1α (HIF-1α) Synthesis: Novel Mechanism for HIF-1-Mediated Vascular Endothelial Growth Factor Expression

Erik Laughner, Panthea Taghavi, Kelly A. Chiles et al. · Molecular and Cellular Biology · 2001 · 1.3K citations · Full text

Life Sciences, Cell Biology, Oncology +17

Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb

Andrew R. Tee, Brendan D. Manning, Philippe P. Roux et al. · Current Biology · 2003 · 1.2K citations · Full text

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mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

Pradip K. Majumder, Phillip G. Febbo, Rachel Bikoff et al. · Nature Medicine · 2004 · 956 citations

Medicine, Oncology, Urology +15

mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E

Diane C. Fingar, Celeste Richardson, Andrew R. Tee et al. · Molecular and Cellular Biology · 2003 · 873 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Characterization of ADAMTS-9 and ADAMTS-20 as a Distinct ADAMTS Subfamily Related to Caenorhabditis elegans GON-1

Robert Somerville, Jean‐Michel Longpré, Katherine A. Jungers et al. · Journal of Biological Chemistry · 2003 · 326 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +14