The landscape of accessible chromatin in mammalian preimplantation embryos

Jingyi Wu, Bo Huang, He Chen, +21

Nature

ChromatinDevelopmental BiologyChromatin RemodelingGeneticsPreimplantation Genetic Testing +5

Mouse totipotent stem cells captured and maintained through spliceosomal repression

Hui Shen, Min Yang, Shiyu Li, +6

Cell

Regenerative MedicineInduced Pluripotent Stem CellSpliceosomal RepressionDevelopmental BiologyMedicine +6

Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome

Jiangbo Lu, Lei Chang, Tong Li, +28

Cell Research

Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer

Shuaishuai Teng, Yang Eric Li, Ming Yang, +17

Cell Research

Tumor BiologyColorectal CancerLiver CancerMedicineCell Biology +1

ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer

Wei Du, S Wang, Qian Zhou, +8

Oncogene

Tumor BiologyGastrointestinal OncologyMedicinePathologyCancer Biology +8

Akt/Protein Kinase B Is Required for Lymphatic Network Formation, Remodeling, and Valve Development

Fei Zhou, Zai Chang, Luqing Zhang, +10

American Journal Of Pathology

Signal TransductionSignaling PathwayCell RegulationCell SignalingReceptor Tyrosine Kinase +10

Substrate stiffness regulates B‐cell activation, proliferation, class switch, and T‐cell‐independent antibody responses in vivo

Yingyue Zeng, Junyang Yi, Zhengpeng Wan, +10

European Journal of Immunology

Isoform Switch of TET1 Regulates DNA Demethylation and Mouse Development

Wenhao Zhang, Weikun Xia, Q. Wang, +17

Molecular Cell

ChromatinLineage PlasticityDevelopmental BiologyIsoform SwitchNatural Sciences +9

HER2/EGFR–AKT Signaling Switches TGFβ from Inhibiting Cell Proliferation to Promoting Cell Migration in Breast Cancer

Fei Huang, Qiaoni Shi, Yuzhen Li, +12

Cancer Research

PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsiveness

Meixiang Yang, Dan Li, Zai Chang, +3

The Journal of Experimental Medicine