Dissecting the catalytic triad of a serine protease

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

On the size of the active site in proteases. I. Papain

Israël Schechter, Arieh Berger · Biochemical and Biophysical Research Communications · 1967 · 5.2K citations

Life Sciences, Biochemistry, Molecular Biology +9

Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA

Mark J. Zoller, Michael J. Smith · Nucleic Acids Research · 1982 · 762 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Selective Chemical Catalysis by an Antibody

Scott J. Pollack, Jeffrey Jacobs, Peter G. Schultz · Science · 1986 · 630 citations

Life Sciences, Biochemistry, Chemistry +17

Catalytic Antibodies

Alfonso Tramontano, Kim D. Janda, Richard A. Lerner · Science · 1986 · 600 citations

Pharmacy, Biotechnology, Immunology +14