Concepedia

Nordic collaborative study of the <i>BARD1</i> Cys557Ser allele in 3956 patients with cancer: enrichment in familial <i>BRCA1</i>/<i>BRCA2</i> mutation-negative breast cancer but not in other malignancies

Sanna‐Maria Karppinen, Rósa B. Barkardóttir, Katja Backenhorn, Thomas Vognbjerg Sydenham, Kirsi Syrjäkoski, Johanna Schleutker, Tarja Ikonen, Katri Pylkäs, Katrin Rapakko, Hannele Erkko,

Journal of Medical Genetics · 2006 · 44 citations · 32 references

DOIFull text

Open access

Abstract

These results provide further evidence that BARD1 Cys557Ser confers a slightly increased risk of breast cancer in women.

References

32

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene <i>BRCA1</i>

Yoshio Miki, Jeffrey Swensen, Donna Shattuck-Eidens et al. · Science · 1994 · 6.1K citations

, , +16

Identification of the breast cancer susceptibility gene BRCA2

Richard Wooster, Graham R. Bignell, Jonathan Lancaster et al. · Nature · 1995 · 3.6K citations

, , +3

Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families

Deborah Ford, Douglas F. Easton, Michael R. Stratton et al. · The American Journal of Human Genetics · 1998 · 3K citations · Full text

Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations

Deborah J. Thompson, Richard S. Houlston, Catherine Phelan · Nature Genetics · 2002 · 1.1K citations · Full text

, , +7

Dynamic Changes of BRCA1 Subnuclear Location and Phosphorylation State Are Initiated by DNA Damage

Ralph Scully, Junjie Chen, Robert Ochs et al. · Cell · 1997 · 908 citations · Full text

, , +7