Concepedia

Brca1 Mutation Risk

BRCA1 Mutation Risk is a genetic risk assessment construct that quantifies the increased susceptibility to breast and ovarian cancers conferred by pathogenic variants in the BRCA1 tumor suppressor gene, distinguishing it from other hereditary cancer risks by its specific association with BRCA1 gene dysfunction.

759

Publications

70.6K

Citations

6.4K

Authors

1.7K

Institutions

Publications per year

2017–2026

135

Parents

Publications

759

The Risk of Cancer Associated with Specific Mutations of<i>BRCA1</i>and<i>BRCA2</i>among Ashkenazi Jews

Jeffery P. Struewing, Patricia Hartge, Sholom Wacholder et al. · New England Journal of Medicine · 1997 · 2.3K citations · Full text

, , +17

Talazoparib in Patients with Advanced Breast Cancer and a Germline <i>BRCA</i> Mutation

Jennifer K. Litton, Hope S. Rugo, Johannes Ettl et al. · New England Journal of Medicine · 2018 · 2.2K citations · Full text

, , +14

Risks of cancer in BRCA1-mutation carriers

Daniel Ford · The Lancet · 1994 · 1.9K citations

, , +12

Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.

Douglas F. Easton, Deborah Ford, D. Timothy Bishop · PubMed · 1995 · 1.6K citations

, , +16

Bilateral Prophylactic Mastectomy Reduces Breast Cancer Risk in <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers: The PROSE Study Group

Timothy R. Rebbeck, Tara M. Friebel, Henry T. Lynch et al. · Journal of Clinical Oncology · 2004 · 1.1K citations

, , +17

1–5 of 759

Authors

6.4K

  1. SA
    Steven A. Narod

    University of Toronto, Canada

    76 publications · 9.5K citations

    44

    h-index

  2. JL
    Jan Lubiński

    Pomeranian Medical University, Poland

    80 publications · 6.8K citations

    43

    h-index

  3. SL
    Susan L. Neuhausen

    City of Hope, United States

    53 publications · 7.3K citations

    39

    h-index

  4. DF
    Douglas F. Easton

    University of Cambridge, United Kingdom

    53 publications · 8K citations

    38

    h-index

  5. DG
    D. Gareth Evans

    University of Manchester, United Kingdom

    50 publications · 6.6K citations

    33

    h-index

1–5 of 6.4K

Institutions

1.7K

  1. University of Toronto

    Toronto, Canada

    49 h-index

    208 publications

    23.7K citations

  2. Pomeranian Medical University

    Szczecin, Poland

    43 h-index

    458 publications

    45.4K citations

  3. University of Pennsylvania

    Philadelphia, United States

    42 h-index

    269 publications

    33.3K citations

  4. University of Utah

    Salt Lake City, United States

    40 h-index

    154 publications

    16.9K citations

  5. Cancer Genetics (United States)

    Rutherford, United States

    39 h-index

    371 publications

    35.8K citations

  6. Dana-Farber Cancer Institute

    Boston, United States

    39 h-index

    208 publications

    20.2K citations

  7. University of Cambridge

    Cambridge, United Kingdom

    39 h-index

    776 publications

    59.7K citations

  8. Women's College Hospital

    Toronto, Canada

    36 h-index

    207 publications

    27.8K citations

1–8 of 1.7K

Venues

  1. Breast Cancer Research and Treatment

    64 publications · 3K citations

    36

    h-index

  2. Journal of Clinical Oncology

    35 publications · 7.3K citations

    31

    h-index

  3. PubMed

    Repository · 34 publications · 4.8K citations

    23

    h-index

  4. JNCI Journal of the National Cancer Institute

    25 publications · 7.6K citations

    23

    h-index

  5. British Journal of Cancer

    BJC · 26 publications · 2.4K citations

    22

    h-index

1–5