Manipulation of Th1/Th2 balance in vivo by adoptive transfer of antigen-specific Th1 or Th2 cells

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

Frederick P. Heinzel, M D Sadick, B J Holaday et al. · The Journal of Experimental Medicine · 1989 · 1.5K citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

IL-12-Deficient Mice Are Defective in IFNγ Production and Type 1 Cytokine Responses

Jeanne Magram, Suzanne E. Connaughton, Rajeev R. Warrier et al. · Immunity · 1996 · 991 citations · Full text

Life Sciences, Genetics, Immunology +15

Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones.

Daniel Cher, Timothy R. Mosmann · The Journal of Immunology · 1987 · 958 citations

Life Sciences, Immunology, Adaptive Immunity +16

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

Jody L. Baron, Joseph A. Madri, Nancy H. Ruddle et al. · The Journal of Experimental Medicine · 1993 · 830 citations · Full text

Life Sciences, Immunology, Neuroscience +17

Recombinant interleukin 12 cures mice infected with Leishmania major.

Frederick P. Heinzel, David S. Schoenhaut, Ronald M. Rerko et al. · The Journal of Experimental Medicine · 1993 · 764 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17