Concepedia

Exposure to 9,10-phenanthrenequinone accelerates malignant progression of lung cancer cells through up-regulation of aldo-keto reductase 1B10

Toshiyuki Matsunaga, Yoshifumi Morikawa, Mariko Haga, Satoshi Endo, Midori Soda, Keiko Yamamura, Ossama El‐Kabbani, Kazuo Tajima, Akira Ikari, Akira Hara

Toxicology and Applied Pharmacology · 2014 · 33 citations · 57 references

DOI

Concepts

References

57

Superoxide Dismutase

Joe M. McCord, Irwin Fridovich · Journal of Biological Chemistry · 1969 · 12.8K citations · Full text

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Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gina M. DeNicola, Florian A. Karreth, Timothy J. Humpton et al. · Nature · 2011 · 2.2K citations · Full text

, , +14

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

Frank Weinberg, Robert B. Hamanaka, William W. Wheaton et al. · Proceedings of the National Academy of Sciences · 2010 · 1.7K citations

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Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer

Anju Singh, Vikas Misra, Rajesh K. Thimmulappa et al. · PLoS Medicine · 2006 · 1K citations · Full text

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Nrf2 Is a Key Transcription Factor That Regulates Antioxidant Defense in Macrophages and Epithelial Cells: Protecting against the Proinflammatory and Oxidizing Effects of Diesel Exhaust Chemicals

Ning Li, Jawed Alam, M.I. Venkatesan et al. · The Journal of Immunology · 2004 · 449 citations

, , +17