Timothy J. Humpton

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gina M. DeNicola, Florian A. Karreth, Timothy J. Humpton et al. · Nature · 2011 · 2.2K citations · Full text

Oncogenic Agent, Oncogene-induced Nrf2 Transcription, Reactive Oxygen Specie +5

A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

Mylène Tajan, Andreas Hock, Julianna Blagih et al. · Cell Metabolism · 2018 · 217 citations · Full text

Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer

Timothy J. Humpton, Brinda Alagesan, Gina M. DeNicola et al. · Cancer Discovery · 2019 · 190 citations · Full text

Caspase-2-Mediated Cleavage of Mdm2 Creates a p53-Induced Positive Feedback Loop

Trudy G. Oliver, Etienne Meylan, Gregory P. Chang et al. · Molecular Cell · 2011 · 161 citations · Full text

Tumor Biology, Caspase-2-mediated Cleavage, Signal Transduction +8

The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance

Deborah R. Caswell, Philippe Gui, Manasi K. Mayekar et al. · Nature Genetics · 2023 · 76 citations · Full text