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Discovery and SAR exploration of a novel series of imidazo[4,5-b]pyrazin-2-ones as potent and selective mTOR kinase inhibitors

Sar ExplorationMedicinal ChemistryDrug TargetNovel SeriesBiochemistryMedicineNatural SciencesRational Drug DesignPharmacotherapyAnti-cancer AgentDrug DevelopmentChemical BiologyPharmacologyDrug Discovery