Metabolites of tryptophan catabolism are elevated in sera of patients with myelodysplastic syndromes and inhibit hematopoietic progenitor amplification

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

Catherine Uyttenhove, Luc Pilotte, Ivan Théate et al. · Nature Medicine · 2003 · 2.3K citations

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An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

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Medicine, Cancer Biology, Oncology +13

Inhibition of  T Cell Proliferation by Macrophage Tryptophan Catabolism

David H. Munn, Ebrahim Shafizadeh, John T. Attwood et al. · The Journal of Experimental Medicine · 1999 · 1.6K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Tryptophan-derived Catabolites Are Responsible for Inhibition of T and Natural Killer Cell Proliferation Induced by Indoleamine 2,3-Dioxygenase

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Inhibition of Allogeneic T Cell Proliferation by Indoleamine 2,3-Dioxygenase–expressing Dendritic Cells

Peter Terness, Thomas M. Bauer, Lars Röse et al. · The Journal of Experimental Medicine · 2002 · 929 citations · Full text

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