Synthesis, biological evaluation and molecular docking studies of stellatin derivatives as cyclooxygenase (COX-1, COX-2) inhibitors and anti-inflammatory agents

Q-SiteFinder: an energy-based method for the prediction of protein-ligand binding sites

Alasdair T. R. Laurie, Robert M. Jackson · Computer applications in the biosciences · 2005 · 1.1K citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +17

A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385

Scott W. Rowlinson, James R. Kiefer, Jeffery J. Prusakiewicz et al. · Journal of Biological Chemistry · 2003 · 347 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents

Chelliah Selvam, Sanjay M. Jachak, Ramasamy Thilagavathi et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 304 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Structural Analysis of NSAID Binding by Prostaglandin H₂ Synthase:  Time-Dependent and Time-Independent Inhibitors Elicit Identical Enzyme Conformations

Barry S. Selinsky, Kushol Gupta, Caroline T. Sharkey et al. · Biochemistry · 2001 · 289 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Aspirin-like Molecules that Covalently Inactivate Cyclooxygenase-2

Amit S. Kalgutkar, Brenda C. Crews, Scott W. Rowlinson et al. · Science · 1998 · 261 citations

Medicine, Medicinal Chemistry, Pharmacology +13