Changes in CD8 and CD4 lymphocyte subsets, T cell proliferation responses and non-survival in the very old: the Swedish longitudinal OCTO-immune study

Telomere length predicts replicative capacity of human fibroblasts.

Richard Allsopp, Homayoun Vaziri, Cam Patterson et al. · Proceedings of the National Academy of Sciences · 1992 · 2.2K citations · Full text

Life Sciences, Biology, Cell Biology +13

Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy".

David N. Posnett, Renu Sinha, Shara Kabak et al. · The Journal of Experimental Medicine · 1994 · 772 citations · Full text

Life Sciences, Cell Biology, Immunology +14

Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes.

Homayoun Vaziri, François Schächter, Irene A. Uchida et al. · PubMed · 1993 · 744 citations

Life Sciences, Genetics, Molecular Genetics +16

AGEING, IMMUNE RESPONSE, AND MORTALITY

IanC Roberts-Thomson, U Youngchaiyud, Senga Whittingham et al. · The Lancet · 1974 · 482 citations

Education, Geriatric Medicine, Immunology +14

Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis

Rita B. Effros, Richard Allsopp, Choy‐Pik Chiu et al. · AIDS · 1996 · 460 citations

Life Sciences, Immunology, Infectious Diseases +15