Clinical Relevance of Gain-Of-Function Mutations of p53 in High-Grade Serous Ovarian Carcinoma

Hyo Jeong Kang, Sung‐Min Chun, Kyu-Rae Kim, Insuk Sohn, Chang Ohk Sung

PLoS ONE · 2013 · 118 citations · 28 references

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Abstract

This study demonstrates that patient with GOF mutp53 is characterized by a greater likelihood of platinum treatment resistance and distant metastatic properties in HGS-OvCa.

References

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