Purity of Spiking Agent Affects Partitioning of Prions in Plasma Protein Purification

Preparation and Properties of Serum and Plasma Proteins. IV. A System for the Separation into Fractions of the Protein and Lipoprotein Components of Biological Tissues and Fluids^1a,b,c,d

E. J. Cohn, L. E. Strong, William L. Hughes et al. · Journal of the American Chemical Society · 1946 · 1.8K citations

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Eight prion strains have PrPSc molecules with different conformations

Jiri Safar, Holger Wille, Vincenza Itri et al. · Nature Medicine · 1998 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +14

Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay

Sarah Joiner, T. Campbell, Melanie Desbruslais et al. · The Lancet · 2001 · 692 citations

Veterinary Medicine, Infectious Diseases, Molecular Biology +16

Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

Martin Vey, Susanne Pilkuhn, Holger Wille et al. · Proceedings of the National Academy of Sciences · 1996 · 517 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Further studies of blood infectivity in an experimental model of transmissible spongiform encephalopathy, with an explanation of why blood components do not transmit Creutzfeldt‐Jakob disease in humans

Paul Brown, Larisa Červen̆áková, Lisa M. McShane et al. · Transfusion · 1999 · 294 citations

Veterinary Medicine, Infectious Diseases, Pathology +13