Concepedia

Activity of crude extract ofRubus crataegifolius roots as a potent apoptosis inducer and DNA topoisomerase I inhibitor

Jihyeon Lee, Yoon-Ah Ham, Sang-Ho Choi, Eun‐Ok Im, Jee H. Jung, Kwang Sik Im, Dong-Kyoo Kim, Ying Xu, Min Wei Wang, Nam Deuk Kim

Archives of Pharmacal Research · 2000 · 10 citations · 29 references

DOI

Concepts

References

29

Participation of p53 protein in the cellular response to DNA damage.

Michael B. Kastan, Onyinye Onyekwere, D Sidransky et al. · PubMed · 1991 · 3.8K citations

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Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Y H Hsiang, Robert Hertzberg, Sidney M. Hecht et al. · Journal of Biological Chemistry · 1985 · 2.4K citations · Full text

, , +15

Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer

David Cunningham, Seppo Pyrhönen, R.D. James et al. · The Lancet · 1998 · 1.3K citations

, , +13

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways.

William G. Nelson, Michael B. Kastan · Molecular and Cellular Biology · 1994 · 838 citations · Full text

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Phase II study of irinotecan combined with cisplatin in patients with previously untreated small-cell lung cancer. West Japan Lung Cancer Group.

Satoshi Kudoh, Yasuhiro Fujiwara, Y Takada et al. · Journal of Clinical Oncology · 1998 · 170 citations

, , +14