R.D. James

Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer

David Cunningham, Seppo Pyrhönen, R.D. James et al. · The Lancet · 1998 · 1.3K citations

Medicine, Oncology, Pharmacotherapy +13

Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2×2 factorial trial

R.D. James, Rob Glynne‐Jones, Helen Meadows et al. · The Lancet Oncology · 2013 · 733 citations · Full text

Medicine, Oncology, Radiation Oncology +12

Epidermoid anal cancer: Results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin

S.J. Arnott, David Cunningham, James Gallagher et al. · Oxford University Research Archive (ORA) (University of Oxford) · 1996 · 727 citations

Medicine, Oncology, Radiation Oncology +8

Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial

Tim Maughan, Jonathan A. Ledermann, C. Topham et al. · The Lancet · 2007 · 568 citations

Medicine, Oncology, Chemotherapy +10

Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I)

John Northover, Rob Glynne‐Jones, David Sebag‐Montefiore et al. · British Journal of Cancer · 2010 · 428 citations · Full text

Medicine, Oncology, Radiation Oncology +10