C. Topham

Oxaliplatin, Fluorouracil, and Leucovorin as Adjuvant Treatment for Colon Cancer

Thierry André, C. Boni, Lamia Mounedji-Boudiaf et al. · New England Journal of Medicine · 2004 · 3.7K citations · Full text

Medicine, Oncology, Surgery +17

Improved Overall Survival With Oxaliplatin, Fluorouracil, and Leucovorin As Adjuvant Treatment in Stage II or III Colon Cancer in the MOSAIC Trial

Thierry André, C. Boni, Matilde Navarro et al. · Journal of Clinical Oncology · 2009 · 2.3K citations

Medicine, Oncology, Surgery +16

Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer

David Cunningham, Seppo Pyrhönen, R.D. James et al. · The Lancet · 1998 · 1.3K citations

Medicine, Oncology, Pharmacotherapy +13

Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial

Tim Maughan, Jonathan A. Ledermann, C. Topham et al. · The Lancet · 2007 · 568 citations

Medicine, Oncology, Chemotherapy +10

Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: a multicentre randomised trial

TS Maughan, RD James, DJ Kerr et al. · The Lancet · 2003 · 190 citations

Medicine, Oncology, Chemotherapy +11