C. Topham

Oxaliplatin, Fluorouracil, and Leucovorin as Adjuvant Treatment for Colon Cancer

Thierry André, C. Boni, Lamia Mounedji-Boudiaf et al. · New England Journal of Medicine · 2004 · 3.6K citations · Full text

Improved Overall Survival With Oxaliplatin, Fluorouracil, and Leucovorin As Adjuvant Treatment in Stage II or III Colon Cancer in the MOSAIC Trial

Thierry André, C. Boni, Matilde Navarro et al. · Journal of Clinical Oncology · 2009 · 2.3K citations

Surgical Oncology, Cancer Management, Pathology +16

Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer

David Cunningham, Seppo Pyrhönen, R.D. James et al. · The Lancet · 1998 · 1.3K citations

Gastrointestinal Oncology, Medicine, Cancer Management +6

Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial

Tim Maughan, Jonathan A. Ledermann, C. Topham et al. · The Lancet · 2007 · 564 citations

Mrc Focus, Surgical Oncology, Different Strategies +7

Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: a multicentre randomised trial

TS Maughan, RD James, DJ Kerr et al. · The Lancet · 2003 · 190 citations

Palliative Care, Continuous Palliative Chemotherapy, Gastrointestinal Oncology +7