RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML)

A simple salting out procedure for extracting DNA from human nucleated cells

S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research · 1988 · 20.4K citations · Full text

Chromatin, Dna Sequencing, Molecular Biological Method +11

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

Masato Orita, Youichi Suzuki, Takao Sekiya et al. · Genomics · 1989 · 3.5K citations

Sensitive Detection, Polymerase Chain Reaction, Genetic Analysis +12

The MAPK signaling cascade

Rony Seger, Edwin G. Krebs · The FASEB Journal · 1995 · 3.4K citations

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

Daniel Pinkel, T. Straume, Joe W. Gray · Proceedings of the National Academy of Sciences · 1986 · 3.2K citations · Full text

Genetic Testing, Engineering, Cytogenetics +18

Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells

Gideon Bollag, D. Wade Clapp, Shane Shih et al. · Nature Genetics · 1996 · 603 citations

Inflammation, Nf1 Results, Signaling Pathway +8